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Amifostine thiol

SKU: orb1692806

Description

Amifostine thiol

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number31098-42-7
MW134.24
Purity≥95.0% (May vary between batches)
FormulaC5H14N2S
SMILESNCCCNCCS
TargetMDM-2/p53,p53,Mdm2
SolubilityH2O:80 mg/mL (595.95 mM);DMSO:200 mg/mL (1489.87 mM)

Bioactivity

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In Vitro
4 mM Amifostine thiol exhibits a protective effect against the genome instability induced by 30 minutes of X-ray irradiation, and also protects RKO36 cells from chromosomal damage and death caused by ionizing radiation.

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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WR-1065, MDM-2/p53, Amifostine thiol

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Quality Guarantee

Quality Guarantee

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Key Properties

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No computed properties available.

Protocol Information