Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

ALK inhibitor 2

SKU: orb1304599

Description

ALK inhibitor 2 is a novel, selective small molecule targeting the anaplastic lymphoma kinase (ALK). It is a valuable research tool for investigating ALK-driven pathologies, such as certain cancers, in both cellular (in vitro) and animal model (in vivo) studies.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

−

Key Properties

−
CAS Number761438-38-4
MW518.03
Purity>99.99% (May vary between batches)
FormulaC23H28ClN7O3S
SMILESCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCN(C)CC2)ncc1Cl
TargetALK,FAK
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.93 mM);DMSO:5.19 mg/mL (10.02 mM)

Bioactivity

−
Target IC50
FAK:5 nM (IC50)|TSSK2:37 nM (IC50)

Storage & Handling

−
Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

−
TSSK2, testis-specific, PTK2, PTK2 protein tyrosine kinase 2, reversible, serine/threonine, kinase, inhibit, Inhibitor, male, FAK, focal, Focal adhesion kinase, ALK, ALK tyrosine kinase receptor, ALK inhibitor 2, ALK inhibitor2, ALK inhibitor-2, adhesion, Anaplastic lymphoma kinase (ALK), Anaplastic lymphoma kinase, contraception, Cluster of differentiation 246, CD246

Similar Products

−
  • F6524-1593 [orb3027622]

    2034409-47-5

    364.36

    C18H16N6O3

    50 mg, 10 mg
  • Ceritinib mesylate [orb3210975]

    2055376-74-2

    750.35

    C30H44ClN5O9S3

    10 mg, 50 mg
  • ALK/HDAC-IN-2 [orb3175039]

    10 mg, 50 mg
  • ALK2-IN-2 [orb1710458]

    99.86% (May vary between batches)

    2254409-25-9

    497.61

    C28H27N5O2S

    25 mg, 50 mg, 100 mg, 1 mg, 5 mg, 10 mg, 200 mg, 1 ml x 10 mM (in DMSO)
  • CEP-14083 [orb1740942]

    856692-39-2

    518.61

    C31H30N6O2

    50 mg, 100 mg, 25 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

−
No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 160.00
2 mg
$ 210.00
5 mg
$ 300.00
10 mg
$ 400.00
25 mg
$ 630.00
50 mg
$ 890.00
100 mg
$ 1,170.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry