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AG1557

SKU: orb1306688

Description

AG1557 is a potent and selective EGFR tyrosine kinase inhibitor with a pIC50 of 8.194. This small molecule is used in biochemical and cellular assays to study EGFR-driven signaling pathways in cancer research, including investigations into cell proliferation and tumor growth.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number189290-58-2
MW407.21
Purity99.23% (May vary between batches)
FormulaC16H14IN3O2
SMILESCOc1cc2ncnc(Nc3cccc(I)c3)c2cc1OC
TargetPotassium Channel,EGFR
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.46 mM);DMSO:4.08 mg/mL (10.02 mM)

Bioactivity

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Target IC50
EGFR:8.194 (pIC50)

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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inhibit, EGFR, Epidermal growth factor receptor, ErbB-1, Inhibitor, HER1, hERG, AG 1557, AG1557, AG-1557

Similar Products

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  • AG-1557 hydrochloride [orb1302645]

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

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No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 70.00
10 mg
$ 90.00
25 mg
$ 120.00
50 mg
$ 170.00
100 mg
$ 240.00
200 mg
$ 340.00
DispatchUsually dispatched within 5-10 working days
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