ABT-281

SKU: orb1701286

Description

ABT-281 is a topical ascomycin-derived macrolactam that potently inhibits T-cell activation. Its optimized profile minimizes systemic exposure, making it a valuable research tool for studying localized immune responses in dermatological and inflammatory disease models, both in vitro and in vivo.

Key Properties

• CAS Number: 148147-65-3
• MW: 844.06
• Formula: C₄₄H₆₉N₅O₁₁
• SMILES: [H][C@]12O[C@](O)([C@H](C)C[C@@H]1OC)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@H]([C@H](C)[C@@H](O)CC(=O)[C@H](CC)\C=C(C)\C[C@H](C)C[C@@H]2OC)C(\C)=C/[C@@H]1CC[C@@H]([C@@H](C1)OC)n1cnnn1 |c:38|
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171360269