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A 65281

SKU: orb1701375

Description

A 65281 is an antibacterial isothiazoloquinolone that potently inhibits the P4-unknotting reaction. It induces significant DNA breakage via calf thymus topoisomerase II, making it a useful tool for studying topoisomerase mechanisms and bacterial enzyme function in vitro.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Images & Validation

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Key Properties

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CAS Number111279-49-3
MW378.4
FormulaC17H16F2N4O2S
SMILESFC1=C2N(C3=C(C(=O)C2=CC(F)=C1N4CCNCC4)C(=O)NS3)C5CC5
TargetAntibacterial,Others,DNA/RNA Synthesis

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

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No computed properties available.

Protocol Information