5,7-Dihydroxychromone

SKU: orb1222371

Description

5, 7-Dihydroxychromone isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 5, 7-Dihydroxychromone exerts neuroprotective effect against 6-OHDA-induced oxidative stress and apoptosis by activating Nrf2/ARE signal. 5, 7-Dihydroxychromone induces the translocation of Nrf2 to the nucleus and increases Nrf2/ARE binding activity which results in the up-regulation of the expression of Nrf2-dependent antioxidant genes, including HO-1, NQO1, and GCLc.

Key Properties

• CAS Number: 31721-94-5
• MW: 178.14
• Purity: >98% (HPLC)
• Formula: C₉H₆O₄
• SMILES: C1=COC2=CC(=CC(=C2C1=O)O)O
• Target: Nrf2
• Solubility: In Vitro: DMSO : 100 mg/mL (561.36 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Nrf2