4-Methoxycinnamaldehyde

SKU: orb1683502

Description

4-Methoxycinnamaldehyde

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 1963-36-6
• MW: 162.19
• Purity: 99.87% (May vary between batches)
• Formula: C₁₀H₁₀O₂
• SMILES: COc1ccc(\C=C\C=O)cc1
• Target: RSV
• Solubility: DMSO:60 mg/mL (369.94 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (30.83 mM)

Bioactivity

• In Vitro:
  4-Methoxycinnamaldehyde could effectively inhibit cytopathic effect of RSV (p<0.0001) with an estimated IC(50) of 0.055microg/ml and a selectivity index (SI) of 898.2. 4-Methoxycinnamaldehyde (0.03microg/ml) could inhibit viral entrance by interfering viral attachment (IC(50) of 0.06microg/ml; p<0.0001) and internalization (IC(50) of 0.01microg/ml; p<0.0001). 4-Methoxycinnamaldehyde significantly increased the basal production of IFN (p=0.0015), but not the virus-induced IFN production. In conclusion, 4-Methoxycinnamaldehyde might be helpful to manage the disease induced by RSV infection.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

4-Methoxycinnamaldehyde, IFN, p-Methoxycinnamaldehyde, RSV

Compound Identifiers

PubChem CID

641294