4-Desmethyl-2-methyl celecoxib

SKU: orb3028585

Description

4-Desmethyl-2-methyl celecoxib is a structural analog of celecoxib. As an orally available, highly selective cyclooxygenase-2 (COX-2) inhibitor (IC50 = 0.069 μM), it exerts anti-inflammatory, analgesic, and antipyretic effects, primarily by reducing prostaglandin synthesis. It is used in research on inflammatory and pain-related conditions such as rheumatoid arthritis and osteoarthritis.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 170569-99-0
• MW: 381.37
• Purity: 99.77% (May vary between batches)
• Formula: C₁₇H₁₄F₃N₃O₂S
• SMILES: O=S(=O)(N)C1=CC=C(C=C1)N2N=C(C=C2C=3C=CC=CC3C)C(F)(F)F
• Target: COX

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

COX