4-Aminonaphthalimide

SKU: orb1306313

Description

4-Amino-1,8-naphthalimide (4-ANI) is a potent small molecule inhibitor of PARP, exhibiting an IC50 value of 180 nM. It is widely used in biochemical research to study DNA repair mechanisms and has been applied in both in vitro assays and in vivo models of cancer and oxidative stress.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 1742-95-6
• MW: 212.2041
• Purity: >98%
• Formula: C₁₂H₈N₂O₂
• SMILES: NC1=C2C=CC=C3C(=O)NC(=O)C(C=C1)=C23
• Target: PARP
• Solubility: DMSO:3.6 mg/mL (16.97 mM)

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

4 amino 1,8 Naphthalimide, 4-Aminonaphthalimide, 4amino1,8Naphthalimide, 4-amino-1,8-Naphthalimide, Inhibitor, inhibit, PARP, poly ADP ribose polymerase

Compound Identifiers

PubChem CID

1720