3-O-Methylquercetin

SKU: orb1297495

Description

3-O-Methylquercetin is a selective, competitive dual inhibitor of PDE3 and PDE4 enzymes, with greater potency against PDE3. It effectively suppresses cAMP and cGMP hydrolysis in guinea pig trachealis, making it a valuable research tool for studying airway smooth muscle physiology and inflammation in vitro.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1486-70-0
• MW: 316.26
• Purity: 99.94% (May vary between batches)
• Formula: C₁₆H₁₂O₇
• SMILES: COc1c(oc2cc(O)cc(O)c2c1=O)-c1ccc(O)c(O)c1
• Target: cAMP,NO Synthase,IL Receptor,PDE

Bioactivity

• Target IC50:
  PDE1-PDE5:1.6-86.9 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cAMP, 3OMethylquercetin, 3-O-Methylquercetin, 3 O Methylquercetin, ILReceptor, IL Receptor, inhibit, PDE4, PDE3, PDE, Inhibitor, Phosphodiesterase (PDE)

Compound Identifiers

PubChem CID

5280681