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PRMT5-IN-41

SKU: orb2646358

Description

PRMT5-IN-41 (compound 130) is an effective orally active inhibitor of PRMT5. It inhibits the hERG ion channel with an IC50 of 1.36 µM.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3034034-32-4
MW477.39
FormulaC22H16F5N5O2
SMILESC(N(C)[C@H]1C=2C(OC1)=CC(C(C(F)(F)F)(F)F)=CC2)(=O)C=3C=C4N5C(C(N)=NC4=CC3)=CN=C5
TargetPotassium Channel,Histone Methyltransferase

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

PRMT5-IN-41 (orb2646358)

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