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Catalog Number | orb1732839 |
---|---|
Category | Antibodies |
Description | In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | 2H8 |
Tested applications | ICC, IHC, WB |
Reactivity | Human |
Isotype | Mouse IgG2a |
Immunogen | Purified recombinant human Protein Phosphatase 4C protein fragments expressed in E.coli. |
Concentration | 1mg/ml |
Dilution range | WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/50-1/200 |
Conjugation | Unconjugated |
MW | Calculated MW: 35 kDa; Observed MW: 35 kDa |
Entrez | 5531 |
UniProt ID | P60510 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3. |
Alternative names | PP4; PPX; PP4C; PPH3; PPP4 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ELISA, FC, ICC, IF, IHC, WB | |
Human | |
Rabbit | |
Polyclonal | |
Unconjugated |
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