PP2A alpha/beta Antibody

• Catalog Number: orb1731499
• Category: Antibodies
• Description: PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: ICC, IHC, IP, WB
• Reactivity: Hamster, Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthetic peptide of human PP2A alpha
• Concentration: 1mg/ml
• Dilution range: IP: 1/20; WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 36 kDa; Observed MW: 36 kDa
• Entrez: 5515
• UniProt ID: P67775
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: PPP2CA; Serine/threonine-protein phosphatase 2A ca
• Note: For research use only
• Expiration Date: 12 months from date of receipt.