pimpinellin

SKU: orb1220780

Description

Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.

Key Properties

• CAS Number: 131-12-4
• MW: 246.22
• Purity: >98% (HPLC)
• Formula: C₁₃H₁₀O₅
• SMILES: COc1c(OC)c2ccc(=O)oc2c2ccoc12
• Target: Antifection
• Solubility: DMSO:49 mg/mL (199.0 mM)

Bioactivity

• In Vitro:
  Pimpinellin has potent cytotoxic activities against the three tumor cells MGC-803, PC3, and A375, with the IC50 values of 14.4±0.3 μM, 20.4±0.5 μM, and 29.2±0.6 μM, respectively. Pimpinellin inhibits the growth of MGC-803 cells via the induction of tumor cell apoptosis, with apoptosis ratio of 27.44% after 72 h of treatment at 20 μM.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Antifection