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Catalog Number | orb147924 |
---|---|
Category | Antibodies |
Description | Mouse monoclonal to Piccolo (APC). Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1.. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | 6H9-B6 |
Tested applications | ELISA, ICC, WB |
Reactivity | Human, Mouse, Rat |
Isotype | IgG2b Kappa |
Immunogen | Full length recombinant protein (GenBank ID: BC001304.1) |
Concentration | 1 mg/ml |
Dilution range | WB (1:1000), ICC/IF (1:100) |
Conjugation | APC |
MW | 550kDa |
Target | Piccolo |
Entrez | 26875 |
UniProt ID | Q9QYX7 |
NCBI | NP_001104266.1 |
Storage | Conjugated antibodies should be stored at 4°C |
Buffer/Preservatives | PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated |
Alternative names | ACZ antibody, Aczonin antibody, PCLO antibody, Pic Read more... |
Note | For research use only |
Application notes | 1 µg/ml of SMC-188 was sufficient for detection of Piccolo in 20 µg of rat brain tissue lysate by colorimetric immunoblot analysis using goat IgG:HRP as the secondary antibody. |
Expiration Date | 12 months from date of receipt. |
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