Piccolo antibody

• Catalog Number: orb147918
• Category: Antibodies
• Description: Mouse monoclonal to Piccolo (ATTO-594). Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1..
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 6H9-B6
• Tested applications: ELISA, ICC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG2b Kappa
• Immunogen: Full length recombinant protein (GenBank ID: BC001304.1)
• Concentration: 1 mg/ml
• Dilution range: WB (1:1000), ICC/IF (1:100)
• Conjugation: ATTO-594
• MW: 550kDa
• Target: Piccolo
• Entrez: 26875
• UniProt ID: Q9QYX7
• NCBI: NP_001104266.1
• Storage: Conjugated antibodies should be stored at 4°C
• Buffer/Preservatives: PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
• Alternative names: ACZ antibody, Aczonin antibody, PCLO antibody, Pic
• Note: For research use only
• Application notes: 1 µg/ml of SMC-188 was sufficient for detection of Piccolo in 20 µg of rat brain tissue lysate by colorimetric immunoblot analysis using goat IgG:HRP as the secondary antibody.
• Expiration Date: 12 months from date of receipt.