PI3-kinase p85-alpha/ gamma (Phospho-Tyr467/199) antibody

• Catalog Number: orb6714
• Category: Antibodies
• Description: Rabbit polyclonal to PI3-kinase p85-alpha/ gamma (Phospho-Tyr467/199). PIK3R1 is a regulatory subunit of phosphoinositide-3-kinase. Mediates binding to a subset of tyrosine-phosphorylated proteins through its SH2 domain. Acts as an adapter, mediating the association of the p110 catalytic unit of the alpha, beta and delta enzymes to the plasma membrane, where p110 phosphorylates inositol lipids. May play an additional role in the regulation of the actin cytoskeleton. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ICC, IF, WB
• Reactivity: Human, Mouse, Rat
• Dilution range: WB:1:500-1:2000, IF/ICC:1:100-1:500
• Conjugation: Unconjugated
• Alternative names: anti GRB1, P85A, PI3-kinase p85-alpha subunit, PI3
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of COS7 whole cell lysates using PI3-kinase p85- alpha/ gamma (Phospho-Tyr467/199) antibody, The lane on the left is treated with the antigen-specific peptide.