Phospho-mTOR (Thr2446) Antibody

• Catalog Number: orb1730604
• Category: Antibodies
• Description: An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: Synthetic peptide of human MTOR
• Dilution range: WB: 1/500-1/1000
• Conjugation: Unconjugated
• MW: Calculated MW: 289 kDa; Observed MW: 220 kDa
• Entrez: 2475
• UniProt ID: P42345
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/thr
• Note: For research use only
• Expiration Date: 12 months from date of receipt.