Phospho-MLKL (Ser358) Mouse Monoclonal Antibody

SKU: orb499999

Description

Phospho-MLKL (Ser358) Mouse Monoclonal Antibody

Images & Validation

• Tested Applications: ICC, IF, IHC-Fr, IHC-P
• Dilution range: IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500
• Reactivity: Human
• Predicted Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG
• Clone No.: 8C4
• Immunogen: KLH conjugated Synthesised monomethylpeptide derived from human MLKL around the phosphorylation site of Ser358 QT(p-S)MS
• Target: MLKL
• Molecular Weight: 54 kDa
• Purification: Affinity purified by Protein G

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Disclaimer: For research use only

Alternative Names

phospho-MLKL(S358); p-MLKL(S358); MLKL(p-S358); hMLKL; Mixed lineage kinase domain like; Mixed lineage kinase domain like protein; Mixed lineage kinase domain-like protein; mixed lineage kinase domain like pseudokinase; MLKL_HUMAN.

Quick Database Links

Gene Symbol

MLKL

UniProt

Q8NB16

References

Khandelwal, Puneet et al. A surfactant polymer wound dressing protects human keratinocytes from inducible necroptosis Sci Rep, 11, 4357 (2021)

PubMed: 33623080

Applications

IHC

Reactivity

Human