Phospho-GSK3 (Tyr279/Tyr216) Antibody

• Catalog Number: orb1730583
• Category: Antibodies
• Description: GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ICC, IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: Synthetic peptide of human GSK3A
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/100-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 51 kDa; Observed MW: 46,51 kDa
• Entrez: 2931
• UniProt ID: P49840
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: Serine/threonine-protein kinase GSK3A
• Note: For research use only
• Expiration Date: 12 months from date of receipt.