Phospho-ERK1/2 (Tyr222/Tyr205) Antibody

• Catalog Number: orb1733144
• Category: Antibodies
• Description: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 5F8
• Tested applications: IHC
• Reactivity: Human, Mouse, Rat
• Isotype: Mouse IgG1
• Immunogen: Synthetic peptide conjugated to KLH.
• Concentration: 1mg/ml
• Dilution range: IHC: 1/50-1/100
• Conjugation: Unconjugated
• Entrez: 5595, 5594
• UniProt ID: P27361, P28482
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: MAPK1/MAPK3
• Note: For research use only
• Expiration Date: 12 months from date of receipt.