Phospho-AKT (Ser473) Antibody

• Catalog Number: orb1733142
• Category: Antibodies
• Description: Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 8C4
• Tested applications: IHC, WB
• Reactivity: Human
• Isotype: Mouse IgG1
• Immunogen: Synthetic peptide conjugated to KLH.
• Concentration: 1mg/ml
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100
• Conjugation: Unconjugated
• MW: Calculated MW: 56 kDa; Observed MW: 60 kDa
• Entrez: 207
• UniProt ID: P31749
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: AKT1; PKB; RAC; RAC-alpha serine/threonine-protein
• Note: For research use only
• Expiration Date: 12 months from date of receipt.