phosphatase and tensin homolog Antibody

• Catalog Number: orb1742522
• Category: Antibodies
• Description: PTEN antibody detects phosphatase and tensin homolog (PTEN), a known tumor suppressor protein with a predicted molecular weight of ~47 kDa. PTEN is a key phosphatase involved in the AKT pathway, playing important roles in cell growth, survival, and migration. Loss of PTEN function is found in various diseases, including cancers.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ICC, IHC-P, WB
• Reactivity: Canine, Feline, Human, Mouse, Porcine, Rat
• Isotype: IgG
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PTEN. The exact sequence is proprietary.
• Concentration: 1.68 mg/ml (Please refer to the vial label for the specific concentration.)
• Dilution range: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
• Form/Appearance: Liquid
• Conjugation: Unconjugated
• MW: 47
• Target: phosphatase and tensin homolog
• UniProt ID: P60484
• Storage: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
• Buffer/Preservatives: 0.025% ProClin 300. 1XPBS (pH7), 20% Glycerol
• Alternative names: phosphatase and tensin homolog , 10q23del , BZS ,
• Note: For research use only
• Application notes: Positive control: NIH-3T3 , 293T , PC-12
• Expiration Date: 12 months from date of receipt.