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Phellopterin

SKU: orb1222456

Description

Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. Phellopterin shows a cytotoxic effect on RAW264.7 cell at the concentration from 40 to 400 μM. Phellopterin reduce TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium.

Images & Validation

Key Properties

CAS Number2543-94-4
MW300.31
Purity>98% (HPLC)
FormulaC17H16O5
SMILESCOc1c2ccoc2c(OCC=C(C)C)c2oc(=O)ccc12
TargetGABA
SolubilityIn Vitro: DMSO : 100 mg/mL (332.99 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Phellopterin (orb1222456)

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200 mg
500 mg
5 mg
$ 240.00
10 mg
$ 390.00
25 mg
$ 640.00
50 mg
$ 900.00
100 mg
$ 1,240.00