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Catalog Number | orb1956309 |
---|---|
Category | Small Molecules |
Description | PFDN2 Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | Approxiamtely 18.5 kDa |
Biological Activity | PFD2, also known as PFDN2, belongs to the prefoldin beta subunit family. PFD2 is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. PFD2 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. PFD2 also binds to a nascent polypeptide chain and promotes folding in a setting in which there are many competing pathways for nonnative proteins. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human PFDN2(Met1-Ser154) was fused with the N-terminal His Tag and expressed in E. coli. |
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