PF-477736 2HCl

SKU: orb2814745

Description

PF-477736 is a potent and selective CHK1 kinase inhibitor used in research to sensitize cancer cells to DNA-damaging chemotherapies. It has demonstrated synergistic effects in preclinical in vitro and in vivo models, particularly in tumors with defective p53 pathways, supporting its investigation in oncology research.

Key Properties

• CAS Number: 1247874-19-6
• MW: 492.4
• Formula: C₂₂H₂₇Cl₂N₇O₂
• SMILES: O=C1C2=C3C(C=NN1)=C(C4=CN(C)N=C4)NC3=CC(NC([C@@H](C5CCCCC5)N)=O)=C2.Cl.Cl

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

154731146