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Catalog Number | orb422334 |
---|---|
Category | Small Molecules |
Description | PF-06726304 is a selective EZH2 inhibitor with Ki values of 0.7 nM and 3 nM for WT EZH2 and Y641N respectively; also inhibits H3K27me3 with the IC50 value of 15 nM. |
CAS Number | [1616287-82-1] |
MW | 446.33 |
SMILES | CC1=CC(=C(C(=O)N1)CN2CCC3=C(C=C(C(=C3C2=O)Cl)C4=C(ON=C4C)C)Cl)C |
Formula | C22H21Cl2N3O3 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
98.30% | |
1616287-82-1 | |
446.33 | |
C22H21Cl2N3O3 |
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