Penicillin G potassium

SKU: orb1301654

Description

Penicillin G potassium is the potassium salt of benzylpenicillin, a broad-spectrum beta-lactam antibiotic. It is widely used in research for its bactericidal activity against Gram-positive bacteria in both in vitro susceptibility assays and in vivo infection model studies.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 113-98-4
• MW: 372.48
• Purity: 96.30% (May vary between batches)
• Formula: C₁₆H₁₇KN₂O₄S
• SMILES: [K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc1ccccc1)C([O-])=O
• Target: Antibacterial,Antibiotic,Anti-infection
• Solubility: DMSO:22.73 mg/mL (61.02 mM);H2O:80 mg/mL (214.78 mM)

Bioactivity

• In Vivo:
  Potassium penicillin G administered in drinking water is effective in reducing mortality associated with S. suis infection and reducing tonsillar carriage of S. suis that may lead to disease and be a source of pig-to-pig transmission of infection.
• Animal Research:
  Fresh stock solution was prepared twice daily by an individual who was not involved with assessment of the study pigs. The test article was administered via the drinking water for 5 d over 2 periods of treatment. The first treatment period commenced on the day of weaning, when the pigs were moved into the nursery barns (Day 1) and ended on Day 5. The second treatment period began on Day 21 and ended on Day 25. The Control group did not receive treatment.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Penicillin G, Penicillin G potassium, Benzylpenicillin potassium, Benzylpenicillin, Antiinfection, Anti-infection, Antibiotic, Bacterial, inhibit, Inhibitor

Compound Identifiers

PubChem CID

23664709