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Catalog Number | orb1733288 |
---|---|
Category | Proteins |
Description | Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. |
Reactivity | Human |
Tag | C-10×His |
Form/Appearance | Powder |
Conjugation | PE |
MW | 42.7 kDa |
Target | IL-1 RAcP |
Source | PE-Labeled Human IL-1 RAcP Protein, His Tag (orb1733288) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Glu 359 (Accession # Q9NPH3-1). |
Expression System | HEK293 |
Expression Region | Ser 21 - Glu 359 |
Storage | -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Buffer/Preservatives | PBS, 0.5%rAlbumin, pH7.4 |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.7 kDa. |
Expiration Date | 6 months from date of receipt. |
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