PDGFA Protein, Canine, Recombinant (His)

• Catalog Number: orb1954714
• Category: Proteins
• Description: Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Canine, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.5 kDa and the accession number is A0A8C0M6T8.
• Tag: N-His
• Purity: 98.00%
• MW: 14.5 kDa (predicted)
• UniProt ID: A0A8C0M6T8
• Expression System: P. pastoris (Yeast)
• Biological Origin: Canine
• Biological Activity: Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Canine, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.5 kDa and the accession number is A0A8C0M6T8.
• Expression Region: A DNA sequence encoding the canine PDGFA (NP_001177101.1) (Ser87-Arg196) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His
• Storage: -20°C
• Note: For research use only
• Application notes: A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
• Expiration Date: 6 months from date of receipt.