PCI-27483

SKU: orb1695177

Description

PCI-27483 is a potent and selective inhibitor of activated coagulation factor VIIa (FVIIa). It demonstrates antithrombotic activity in a baboon arterial thrombosis model and significantly inhibits the growth of BxPC3 pancreatic tumor xenografts in vivo, supporting its investigation in thrombosis and oncology research.

Research Area

Metabolism Research

Key Properties

• CAS Number: 871266-63-6
• MW: 596.57
• Purity: 99.92% (May vary between batches)
• Formula: C₂₆H₂₄N₆O₉S
• SMILES: NC(=N)c1ccc2[nH]c(nc2c1)-c1cc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc(c1O)-c1cc(ccc1O)S(N)(=O)=O
• Target: Factor VIIa,Others
• Solubility: DMSO:45 mg/mL (75.43 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.35 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, PCI 27483, PCI27483, PCI-27483, Inhibitor, coagulation factor VIIa

Compound Identifiers

PubChem CID

135425273