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Catalog Number | orb613839 |
---|---|
Category | Antibodies |
Description | Rabbit monoclonal antibody to Paxillin (LD2 Motif) |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | LD2 sAB |
Tested applications | ELISA, WB |
Reactivity | Human |
Isotype | IgG |
Immunogen | Peptide corresponding to paxillin-LD2 motif (residues 141-156) fused to MBP; peptide sequence: NLSELDRLLLELNAVQHNP. |
Concentration | 1 mg/ml |
Purity | Purified |
Conjugation | Unconjugated |
Target | Paxillin (LD2 Motif) |
UniProt ID | P49023 |
Storage | Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. |
Buffer/Preservatives | PBS with 0.02% Proclin 300. |
Alternative names | PXN Read more... |
Note | For research use only |
Application notes | This antibody binds to the LD2-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling. |
Expiration Date | 12 months from date of receipt. |
Blocking, ELISA, WB | |
Human | |
Mouse | |
Recombinant | |
Unconjugated |
ELISA, FC, IP | |
Human | |
Rabbit | |
Recombinant | |
Unconjugated |
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