Cart summary

You have no items in your shopping cart.

PAX8 Antibody

Catalog Number: orb750061

DispatchUsually dispatched within 5-10 working days
$ 410.00
Catalog Numberorb750061
CategoryAntibodies
DescriptionPAX-8 is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
Species/HostMouse
ClonalityMonoclonal
Clone NumberPAX8/1491
Tested applicationsIHC-P, WB
ReactivityHuman
IsotypeMouse IgG2b, kappa
ImmunogenA human recombinant fragment (aa 60-261) was used as the immunogen for the PAX-8 antibody.
Antibody TypePrimary Antibody
Dilution rangeWestern blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
PurityProtein G affinity chromatography
ConjugationUnconjugated
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Hazard InformationThis PAX-8 antibody is available for research use only.
UniProt IDQ06710
StorageStore the PAX-8 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Buffer/Preservatives0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
NoteFor research use only
Application notesOptimal dilution of the PAX-8 antibody should be determined by the researcher.
Expiration Date12 months from date of receipt.
PAX8 Antibody

Western blot testing of 1) human partial recombinant protein and 2) human Raji cell lysate with PAX-8 antibody (clone PAX8/1491). Predicted molecular weight of isoforms 1-5: 31, 35, 42, 43 and 48 kDa, respectively. PAX-8 can also be observed at ~62 kDa.

  • PPAR gamma Rabbit Polyclonal Antibody [orb11291]

    FC,  ICC,  IF,  IHC-Fr,  IHC-P,  WB

    Bovine, Gallus, Porcine, Rabbit, Sheep

    Human, Mouse, Rat

    Rabbit

    Polyclonal

    Unconjugated

    100 μl, 200 μl, 50 μl
  • Phospho-PPAR Gamma (Ser112) Rabbit Polyclonal Antibody [orb99282]

    ELISA,  FC,  ICC,  IF,  IHC-Fr,  IHC-P,  WB

    Canine, Guinea pig, Porcine

    Human, Mouse, Rabbit, Rat

    Rabbit

    Polyclonal

    Unconjugated

    100 μl, 200 μl, 50 μl
  • Phospho-PPAR Gamma (ser273) Rabbit Polyclonal Antibody [orb158188]

    ELISA,  WB

    Bovine, Gallus, Mouse, Rabbit, Rat, Sheep

    Human

    Rabbit

    Polyclonal

    Unconjugated

    50 μl, 100 μl, 200 μl
  • PAX8 antibody [orb555967]

    ChIP,  ICC,  IHC,  IHC-P,  IP,  WB

    Canine, Human, Mouse, Rat

    Rabbit

    Polyclonal

    Unconjugated

    100 μl
  • PAX8 Rabbit Polyclonal Antibody [orb11241]

    FC,  ICC,  IF,  IHC-Fr,  IHC-P

    Bovine, Canine, Goat, Mouse, Sheep

    Human, Rat

    Rabbit

    Polyclonal

    Unconjugated

    100 μl, 200 μl, 50 μl