Patulin

SKU: orb1303540

Description

Patulin is a mycotoxin produced by Aspergillus and Penicillium molds, commonly associated with spoiled apples. It is widely used in research as a tool to study cytotoxicity, oxidative stress, and mitochondrial dysfunction in various in vitro cellular models.

Research Area

Cell Biology

Key Properties

• CAS Number: 149-29-1
• MW: 154.12
• Purity: >98%
• Formula: C₇H₆O₄
• SMILES: OC1OCC=C2OC(=O)C=C12
• Target: ER/Golgi
• Solubility: Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).

Bioactivity

• In Vivo:
  The oral LD50 value of patulin ranges between 29 and 55 mg/kg body weight in rodents and 170 mg/kg body weight in poultry.
• In Vitro:
  The World Health Organization considers patulin cytotoxic and established a safety level of patulin in apple juice at 50 μM.2 At 100-200 μM, patulin can directly increase intracellular oxidative stress in HEK293 and HL-60 cells.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Clavacin; Mycoin; Penicidin; Terinin; NSC8120

Compound Identifiers

PubChem CID

4696