PARP3 antibody

• Catalog Number: orb106961
• Category: Antibodies
• Description: Rabbit polyclonal to PARP3. Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Clone Number: RB42819
• Tested applications: WB
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: Synthetic Peptide
• Dilution range: WB: 1:1000
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• MW: 60089
• Target: PARP3
• UniProt ID: Q9Y6F1
• NCBI: NP_005476.3, NP_001003931.2
• Alternative names: anti PARP3 antibody, anti ADPRT3 antibody, anti AD
• Note: For research use only
• Expiration Date: 12 months from date of receipt.