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PARP1/BRD4-IN-3

SKU: orb2664990

Description

PARP1/BRD4-IN-3 (HF4) is a dual inhibitor of BRD4 and PARP1 with IC50 values of 1210 nM and 2019 nM, respectively. It demonstrates anti-proliferative effects by inducing apoptosis, G0/G1 phase arrest, DNA damage, and reducing Rad51 expression in vitro, supporting its investigation in oncology research.

Research Area

Cell Biology, Epigenetics & Chromatin, Epigenetics & Chromatin; Cell Biology, Molecular Biology

Images & Validation

Key Properties

TargetEpigenetic Reader Domain|||PARP|||Apoptosis|||DNA/RNA Synthesis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information