PARP-1-IN-23

SKU: orb2646064

Description

PARP-1-IN-23 (Compound I16) is a potent and selective PARP-1 inhibitor with an IC50 of 12.38 nM, demonstrating oral bioavailability. It is a valuable research tool for investigating DNA damage response pathways and has shown efficacy in suppressing tumor growth in preclinical in vivo models.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 2976497-48-8
• MW: 516.36
• Formula: C₂₂H₁₈BrN₃O₅S
• SMILES: O=C(N)C=1C=CC=C2N=C(NC21)C=3C=C(Br)C(OS(=O)(=O)C=4C=CC=CC4C)=C(OC)C3
• Target: PARP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172638530