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PAP Protein, Human, Recombinant (His)
Catalog Number: orb1961219
| Catalog Number | orb1961219 |
|---|---|
| Category | Proteins |
| Description | Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha. |
| Tag | N-6xHis |
| Purity | 98.00% |
| MW | 30 KDa (reducing condition) |
| UniProt ID | Q13442 |
| Protein Sequence | Met1-Lys181 |
| Expression System | E. coli |
| Biological Origin | Human |
| Biological Activity | Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha. |
| Expression Region | Met1-Lys181 |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 6 months from date of receipt. |
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> 95% as determined by SDS-PAGE
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98.00%
50 KDa (reducing condition)
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