p21 Cip1 (Phospho-Thr145) antibody

• Catalog Number: orb106145
• Category: Antibodies
• Description: Rabbit polyclonal to p21 Cip1 (Phospho-Thr145). This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: IHC-P, WB
• Reactivity: Human, Mouse, Rat
• Dilution range: WB:1:500-1:2000, IHC-P:1:50-1:200
• Conjugation: Unconjugated
• Alternative names: anti CAP20 antibody, anti CDK-interacting protein
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

References

Lehmann, Kuno et al. Liver failure after extended hepatectomy in mice is mediated by a p21-dependent barrier to liver regeneration Gastroenterology, 143, 1609-1619.e4 (2012)

PubMed: 22960658

Western blot analysis of EGF treated HeLa whole cell lysates using p21 Cip1 -Phospho-Thr145- antibody