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Catalog Number | orb1731580 |
---|---|
Category | Antibodies |
Description | Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. |
Species/Host | Rabbit |
Clonality | Monoclonal |
Tested applications | ICC, IHC, IP, WB |
Reactivity | Human |
Isotype | Rabbit IgG |
Immunogen | A synthetic peptide of human p150 CAF1 |
Concentration | 1mg/ml |
Dilution range | IP: 1/20; WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/50-1/200 |
Conjugation | Unconjugated |
MW | Calculated MW: 107 kDa; Observed MW: 150 kDa |
Entrez | 10036 |
UniProt ID | Q13111 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin |
Alternative names | CHAF1A; CAF; CAF1P150; Chromatin assembly factor 1 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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