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Oroxin B

SKU: orb1222851

Description

Oroxin B has antioxidant activity.

Images & Validation

Key Properties

CAS Number114482-86-9
MW594.52
Purity>98% (HPLC)
FormulaC27H30O15
SMILESc1(cc(=O)c2c(c(c(cc2o1)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)O)O)c1ccccc1
TargetOthers
SolubilityIn Vitro: DMSO : 100 mg/mL (168.20 mM)

Bioactivity

In Vivo
Animal model: Human lymphoma cell (Raji cell) xenograft model. Dosage: 30 mg/kg. Administration: i.p. , 28 days. Result: Induced malignant lymphoma cell ER stress. Inhibited tumor growth. Prolonged overall survival of tumor-bearing mice. Animal model: HFD-fed rats. Dosage: 200 mg/kg/day. Administration: oral gavage. Result: Reduced the levels of plasma lipids, LPS, IL-6, and TNF-α. Inhibited liver fibrosis by reducing collagen deposition.
In Vitro
RT-PCR Cell line: Raji cells. Concentration: 0-40 μM. Incubation time: 48 h. Result: Decreased ER stress master genes (GRP78 and ATF6) mRNA level.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Oroxin B (orb1222851)

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% DMSO +
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% Tween 80 +
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100 mg
200 mg
500 mg
5 mg
$ 550.00
10 mg
$ 750.00
25 mg
$ 1,350.00