Obacunone

SKU: orb1304247

Description

Obacunone is a bioactive small molecule with demonstrated cytotoxicity in androgen-dependent prostate cancer cells and antivirulence activity against Salmonella Typhimurium. Research also indicates its potential in breast cancer studies through aromatase inhibition, anti-inflammatory effects, and apoptosis induction, supporting its use in both in vitro and in vivo mechanistic research.

Research Area

Cell Biology, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 751-03-1
• MW: 454.51
• Purity: 99.92% (May vary between batches)
• Formula: C₂₆H₃₀O₇
• SMILES: C[C@@]12CC[C@@H]3[C@@]4(C)C=CC(=O)OC(C)(C)[C@@H]4CC(=O)[C@@]3(C)[C@]11O[C@@H]1C(=O)O[C@H]2c1ccoc1
• Target: Aromatase,p38 MAPK,Apoptosis
• Solubility: DMSO:250 mg/mL (550.04 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.26 mM);Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;50% PEG300+50% Saline:1 mg/mL (2.2 mM)

Bioactivity

• Target IC50:
  Aromatase:28.4 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, p38MAPK, p38 MAPK, Obacunone, Inhibitor, Apoptosis, Aromatase

Compound Identifiers

PubChem CID

119041