NVP-LDE225(Erismodegib)

• Catalog Number: orb320178
• Category: Small Molecules
• Description: LDE225 (NVP-LDE225) is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively. Phase 3.
• CAS Number: [956697-53-3]
• MW: 485.498
• SMILES: FC(OC1C([H])=C([H])C(=C([H])C=1[H])C1C([H])=C([H])C([H])=C(C(N([H])C2=C([H])N=C(C([H])=C2[H])N2C([H])([H])[C@]([H])(C([H])([H])[H])O[C@]([H])(C([H])([H])[H])C2([H])[H])=O)C=1C([H])([H])[H])(F)F
• Formula: C₂₆H₂₆F₃N₃O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.