NVP-BEZ235

• Catalog Number: orb154684
• Category: Small Molecules
• Description: BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM.
• CAS Number: [915019-65-7]
• MW: 469.5365
• SMILES: O=C1N(C([H])([H])[H])C2=C([H])N=C3C([H])=C([H])C(C4C([H])=NC5=C([H])C([H])=C([H])C([H])=C5C=4[H])=C([H])C3=C2N1C1C([H])=C([H])C(=C([H])C=1[H])C(C#N)(C([H])([H])[H])C([H])([H])[H]
• Formula: C₃₀H₂₃N₅O
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of NVP-BEZ235