NUC-7738

• Catalog Number: orb2278564
• Category: Small Molecules
• Description: NUC-7738 is a 5'-aryloxyphosphoamidate prodrug of 3'-dA that reduces β-catenin nuclear expression in AML cells, modulates β-catenin signaling, and can be used in cancer research.
• CAS Number: 2348493-39-8
• Purity: 97.32%
• MW: 568.52
• SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OC4=CC=CC=C4)(N[C@H](C(OCC5=CC=CC=C5)=O)C)=O)C1
• Formula: C₂₆H₂₉N₆O₇P
• Biological Activity: NUC-7738, a 5′-aryloxy phosphoramidate prodrug of 3′-deoxyadenosine (3′-dA), exhibits potent cytotoxic activity against various hematological cancer cell lines and is utilized in cancer research [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.