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Catalog Number | orb342243 |
---|---|
Category | Small Molecules |
Description | NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway.The EC50 of NSC59984 in most cancer cells is significantly lower than those of normal cells, with EC50 of 8.38 μM for p53-null HCT116 cells. |
CAS Number | [803647-40-7] |
MW | 265.27 |
SMILES | CN1CCN(CC1)C(=O)/C=C/C2=CC=C(O2)[N+](=O)[O-] |
Formula | C12H15N3O4 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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