NSC 23766

SKU: orb1690302

Description

NSC 23766

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 733767-34-5
• MW: 421.58
• Purity: 99.49%
• Formula: C₂₄H₃₅N₇
• SMILES: N=1C(=NC(=CC1NC=2C=CC=3N=C(C=C(N)C3C2)C)C)NC(C)CCCN(CC)CC
• Target: Rho,AChR,Ras
• Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.83 mM);DMSO:80 mg/mL (189.76 mM)

Bioactivity

• In Vivo:
  Treatment of NOD mice with NSC 23766 (2.5 mg/kg/day, intraperitoneal injection) significantly slowed the onset of spontaneous diabetes in NOD mice and had no significant effect on the growth (body weight) of the mice.
• In Vitro:
  Treatment of oocytes with NSC 23766 (200 μM) increased the percentage of oocytes with abnormal spindle morphology and significantly decreased the expression of p-MAPK protein.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NSC 23766, NSC23766, NSC-23766

Compound Identifiers

PubChem CID

409805