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Catalog Number | orb1961432 |
---|---|
Category | Small Molecules |
Description | NPR3 Protein, Human, Recombinant (hFc) |
Purity | 98.00% |
MW | 90-100 KDa, reducing conditions |
Biological Activity | Atrial Natriuretic Peptide Receptor-3 (NPR3), also known as NPRC or ANPR-C, is one of the three natriuretic peptide receptors, is a type I transmembrane glycoprotein. The natriuretic system is key to the maintenance of vascular tone and cardiovascular homeostasis. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Osteocrin was found to be a specific ligand to NPR3. NPR3 is necessary for Osteocrin to regulate femoral, tibial, and metatarsal bone elongation. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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