NPE-caged-ATP

SKU: orb63306

Description

NPE-caged-ATP

Images & Validation

• Application Notes:
  Determination of quantum yield and irradiation conditions. Time resolved solid state NMR Ligand for purinergic receptors: The nucleotide can be transported extra-or intracellular in a protected form to the target. After activation by well-defined conditions the liberated ATP can interact with P2X-and P2Y-receptors. Agonistic ligand, mainly for nucleoside receptor A1 Nucleoside-triphosphates can be converted by different membrane-bound phosphatases into nucleosides acting as nucleoside receptor ligands. The caged form is protected during uptake and transport in animal experiments and can be well-directed released through activation at the target tissue. ; Spectroscopic Propertie: λmax 260 nm, ε 18.0 L mmol-1 cm-1 (Tris-HCl, pH 7.5).

Key Properties

• CAS Number: 67030-27-7
• MW: Theoretical MW: 656.33 g/mol (free acid); Detected MW: 656.04 g/mol (free acid)
• Purity: ≥ 95% (HPLC)
• Formula: C₁₈H₂₃N₆O₁₅P₃
• SMILES: [C@@H]1([C@H]([C@@H](O[C@@H]1COP(=O)(OP(=O)(OP(=O)(OC(c1ccccc1[N+](=O)[O-])C)O)O)O)n1c2c(nc1)c(ncn2)N)O)O

Storage & Handling

• Storage: store at -20 °C
• Disclaimer: For research use only