Notoginsenoside R1

SKU: orb1221774

Description

Notoginsenoside R1 has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.

Key Properties

• CAS Number: 80418-24-2
• MW: 933.13
• Purity: >98% (HPLC)
• Formula: C₄₇H₈₀O₁₈
• SMILES: [C@@H]1([C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O[C@@](C)(CCC=C(C)C)[C@H]1CC[C@]2([C@@]3(C[C@@H]([C@H]4C([C@H](CC[C@@]4([C@H]3C[C@H]([C@H]12)O)C)O)(C)C)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@H]1[C@@H]([C@H]([C@@H](CO1)O)O)O)C)C
• Target: ERK1| ERK2
• Solubility: DMSO : ≥ 100 mg/mL; 107.17 mM

Bioactivity

• In Vivo:
  Animal model: Male Sprague-Dawley (SD) rats (200-250 g). Dosage: 5 mg/kg/h. Administration: Infused 20 min before LPS infusion via the right jugular vein. Result: Ameliorated the LPS-induced reduction in the mesenteric venular shear rate to some extent. Attenuated the LPS-induced adhesion of leukocytes to the venular wall. Inhibited mast cell degranulation and cytokine elevation.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Sanchinoside R1 | Sanqi glucoside R1

Quick Database Links

Gene Symbol

ERK1| ERK2